1. The vital capacity can be used to help differentiate causes of lung disease. 2. Several studies have been made to measure and predict vital capacity . 3. The summed total of forced inspiration and expiration is a person's vital capacity . 4. The maximum volume of breath that can be exhaled is called the vital capacity . 5. In restrictive lung disease the vital capacity is decreased. 6. In 1814 John Hutchinson invented the spirometer, which allowed the measurement of vital capacity of the lungs. 7. An airway restriction would not produce a reduced FEV1 / FVC ratio, but would reduce the vital capacity . 8. In study 004, pirfenidone reduced decline in forced vital capacity ( FVC ) ( p = 0.001 ). 9. It reached its maximum about five minutes after the injection, coinciding with the maximum depression of the vital capacity . 10. This manifests as a reduction in lung volumes, particularly the vital capacity ( VC ) and total lung capacity ( TLC ).